The Effect of X-Rays of Different Qualities on The Alkaline Phosphatase of Living Mouse Bone: II. Effects of 22.5-Mevp X-Rays

Abstract

The previously published work on the phosphatase loss in the bones of male mice caused by exposure to 180 kevp and 1000 kevp X-rays was repeated, using female mice. The absolute effect in the females was slightly greater than in the males, but the relative effects of 180 kevp and 1000 kevp x-rays was the same. A similar study was made of the effect of 22.5 Mevp X-rays on the bones of female mice. Further study was made of the chemical composition and spatial relationships of the structures in mouse bone, so that more satisfactory calculation of energy absorption could be made. In the phosphatase-bearing areas the rad/roentgen ratio was: 180 kevp, 1.31; 1000 kevp, 0.92; 22.5 Mevp, 0.95. The R.B.E. of X-rays of 3 qualities for phosphatase loss integrated over the first 50 days after exposure was found to be: 180 kevp, 1.00: 1000 kevp, 1.02; 22.5 Mevp, 1.09. None of these R.B.E. values differs significantly from unity in view of the experimental uncertainties.