Increased thymic hormone responsive suppressor T lymphocyte function in chronic active hepatitis

Abstract
Mitogen-induced suppressor T lymphocyte function was evaluated in patients with chronic active hepatitis (CAH). Thein vitro effect of the biological response modifier, thymosin fraction 5, on the suppressive activity of peripheral blood mononuclear cells (PBM) was also assessed. Suppressor cell activity was significantly decreased in patients with CAH when compared to controls (PPin vitro restoration of suppressor T cell function in patients with CAH.