Guided bone tissue elaboration by osteogenic cells in vitro
- 1 April 1993
- journal article
- research article
- Published by Wiley in Journal of Biomedical Materials Research
- Vol. 27 (4), 429-431
- https://doi.org/10.1002/jbm.820270403
Abstract
Primary rat bone marrow cells were cultured for 2 weeks in polystyrene dishes whose surfaces had been roughened using 600‐ or 320‐grit silicon carbide paper. Eight samples were prepared of each of the three groups of dishes, to include a nontreated control suface. Following the culture period, the dishes were stained by von Kossa's method. The distribution of bone formed during the culture period was examined by light microscopy and the area of bone formed quantified. Results demonstrated that both the amount and spatial distribution of bone were influenced by the roughness of the underlying substratum. Differences between the smooth and roughened surfaces were statistically different at P < .05. © 1993 John Wiley & Sons, Inc.Keywords
This publication has 4 references indexed in Scilit:
- Effects of a grooved titanium‐coated implant surface on epithelial cell behavior in vitro and in vivoJournal of Biomedical Materials Research, 1989
- The effect of surface macrotexture and hydroxylapatite coating on the mechanical strengths and histologic profiles of titanium implant materialsJournal of Biomedical Materials Research, 1987
- Cell responses to biomaterials I: Adhesion and growth of vascular endothelial cells on poly(hydroxyethyl methacrylate) following surface modification by hydrolytic etchingJournal of Biomedical Materials Research, 1987
- Effect of the surface geometry of smooth and porous‐coated titanium alloy on the orientation of fibroblasts in vitroJournal of Biomedical Materials Research, 1987