Molecular cloning, expression and characterization of the human serine/threonine kinase Akt‐3
Open Access
- 1 October 1999
- journal article
- research article
- Published by Wiley in European Journal of Biochemistry
- Vol. 265 (1), 353-360
- https://doi.org/10.1046/j.1432-1327.1999.00774.x
Abstract
Akt (also known as PKB or RAC‐PK) is an intracellular serine/threonine kinase involved in regulating cell survival. Although this makes it a promising target for the discovery of drugs to treat human...Keywords
This publication has 40 references indexed in Scilit:
- Integrins and anoikisCurrent Opinion in Cell Biology, 1997
- Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death MachineryCell, 1997
- PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyondTrends in Biochemical Sciences, 1997
- Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathwayThe EMBO Journal, 1997
- Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinaseProceedings of the National Academy of Sciences, 1997
- The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.Genes & Development, 1997
- Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKBNature, 1997
- Regulation of Neuronal Survival by the Serine-Threonine Protein Kinase AktScience, 1997
- Disruption of epithelial cell-matrix interactions induces apoptosisThe Journal of cell biology, 1994
- The extracellular matrix as a cell survival factor.Molecular Biology of the Cell, 1993