Portal vein thrombosis with ruptured oesophageal varices as presenting manifestation of hereditary protein C deficiency.
Open Access
- 1 June 1988
- Vol. 29 (6), 856-859
- https://doi.org/10.1136/gut.29.6.856
Abstract
The protein C system is essential in limiting the activation of coagulation in vivo. We report the case of a 45 year old man with portal vein thrombosis complicated by ruptured oesophageal varices. Low concentration of plasma protein C was found in the patient and subsequently in one brother with a history of venous thromboembolism, and also in one son and one nephew who were asymptomatic. Hereditary protein C deficiency should be considered in patients with portal hypertension due to portal vein thrombosis.Keywords
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