14 children with central nervous system gangliogliomas are reviewed. The tumors were most frequently located in the cerebral hemisphere and often were cystic and calcified. Total removal was performed in only 1 patient. A well-defined plane of cleavage could not be obtained in the majority of tumors at surgery. All patients are alive on follow-up and only 1 is neurologically disabled. Radiation therapy was given to 4 patients postoperatively. The clinical course of patients given postoperative radiation therapy was not different from that of those who were not irradiated. The histological aspects of the tumors are described.