Coordinate Regulation of 3-Hydroxy-3-methylglutaryl-coenzyme A Synthase, 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase, and Prenyltransferase Synthesis but Not Degradation in HepG2 Cells
Open Access
- 1 July 1989
- journal article
- research article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 264 (21), 12653-12656
- https://doi.org/10.1016/s0021-9258(18)63906-7
Abstract
No abstract availableThis publication has 25 references indexed in Scilit:
- Identification and Regulation of a Rat Liver cDNA Encoding Farnesyl Pyrophosphate SynthetaseJournal of Biological Chemistry, 1989
- Multiple sterol regulatory elements in promoter for hamster 3-hydroxy-3-methylglutaryl-coenzyme A synthase.Journal of Biological Chemistry, 1988
- Multivalent control of 3-hydroxy-3-methylglutaryl coenzyme A reductase. Mevalonate-derived product inhibits translation of mRNA and accelerates degradation of enzyme.Journal of Biological Chemistry, 1988
- Operator constitutive mutation of 3-hydroxy-3-methylglutaryl coenzyme A reductase promoter abolishes protein binding to sterol regulatory element.Journal of Biological Chemistry, 1988
- Optional exon in the 5'-untranslated region of 3-hydroxy-3-methylglutaryl coenzyme A synthase gene: conserved sequence and splicing pattern in humans and hamsters.Proceedings of the National Academy of Sciences, 1987
- Human 3-hydroxy-3-methylglutaryl coenzyme A reductase. Conserved domains responsible for catalytic activity and sterol-regulated degradation.Journal of Biological Chemistry, 1985
- 5′ end of hmg CoA reductase gene contains sequences responsible for cholesterol-mediated inhibition of transcriptionCell, 1985
- Alterations in the rates of synthesis and degradation of rat liver 3-hydroxy-3-methylglutaryl coenzyme A reductase produced by cholestyramine and mevinolin.Journal of Biological Chemistry, 1983
- Isolation and characterization of a photoaffinity-labeled peptide from the catalytic site of prenyltransferaseBiochemistry, 1981
- Biological Activity of Some Oxygenated SterolsScience, 1978