RABBIT POX
Open Access
- 1 September 1935
- journal article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 62 (3), 305-329
- https://doi.org/10.1084/jem.62.3.305
Abstract
The epidemiological significance of age, race, sex, genetic constitution and physiological status were studied by means of a differential analysis of the mortality data derived from a devastating epidemic of rabbit pox and, with the exception of sex, were found to be factors of the utmost importance in the determination of susceptibility. Young animals were more susceptible than adults and although the most susceptible age varied with the epidemic phase, it corresponded in general with the period of weaning. The influence of physiological status was further indicated by the increased susceptibility incident to lactation. Racial variations in susceptibility were obscured by age factors in young animals, but were of profound importance in the adult population and formed the most significant feature of the analysis. A high degree of conformity was found in the susceptibility of racially related breeds, and this similarity in behavior increased with the proximity of relationship. Moreover, a study of the hybrids obtained from the crossing of pure breeds showed that two separable groups of hereditary factors were concerned in the determination of breed susceptibility, one group consisting of essential racial characters, the other of constitutional factors incorporated in the stock by chance association, and that the final expression of susceptibility or resistance was the result of their combined interaction.Keywords
This publication has 4 references indexed in Scilit:
- RABBIT POXThe Journal of Experimental Medicine, 1935
- A Lethal Mutation in the Rabbit with Stigmata of an Acromegalic DisorderScience, 1935
- A Lethal Dwarf Mutation in the Rabbit with Stigmata of Endocrine AbnormalityScience, 1934
- THE REACTION OF STANDARD BREEDS OF RABBITS TO EXPERIMENTAL SYPHILISThe Journal of Experimental Medicine, 1933