Outcome of mechanical ventilation in children with acquired immunodeficiency syndrome
- 1 January 1989
- journal article
- research article
- Published by Wiley in Pediatric Pulmonology
- Vol. 7 (4), 230-234
- https://doi.org/10.1002/ppul.1950070408
Abstract
We retrospectively reviewed the records of 18 children with acquired immunodeficiency syndrome (AIDS) who required mechanical ventilation for respiratory failure. These patients represented 35% of the patients seen with pulmonary disease and AIDS. The most common causes of respiratory failure were Pnuemocystis carinii pneumonia (77%) and bacterial pneumonia (33%). Bronchial lavage by fiberoptic bronchoscopy or endotracheal tube suctioning in mechanically ventilated children with AIDS had a high yield for P. carinii. Eight of 18 (44%) children survived the episode of respiratory failure and were weaned from the ventilator. However, four of eight survivors died within 6 months. Arterial oxygen tension on admission and maximum peak inspiratory pressure on the ventilator did not differ between survivors and non-survivors. We conclude that children with AIDS who are mechanically ventilated can be weaned from the respirator but that the subsequent course remains poor. Pediatr Pulmonol 1989; 7:230–234.Keywords
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