Response to oral administration of pteroylmonoglutamic acid or pteroylpolyglutamate in newborn infants of low birth weight

Abstract

1. Newborn infants of low birth weight absorb both pteroylmonoglutamic acid and pteroylpolyglutamate. 2. There was a significant fall in serum folate concentrations during the first 14 d of life in these infants, but a daily supplement of 50 μg pteroylmonoglutamic acid or pteroylpolyglutamate was sufficient to prevent the development of subnormal serum folate concentrations.