Distribution of HPV types associated with cervical cancers in Scotland and implications for the impact of HPV vaccines
Open Access
- 9 February 2010
- journal article
- research article
- Published by Springer Nature in British Journal of Cancer
- Vol. 102 (5), 930-932
- https://doi.org/10.1038/sj.bjc.6605556
Abstract
This study evaluated human papillomavirus (HPV) type prevalence in 370 Scottish invasive cervical cancers (ICCs) using HPV genotyping and HPV mRNA detection. HPV 16 and/or 18 was detected in 72% of cancers overall and in 82% of HPV-positive cancers. HPV 45 and 16 were the most frequently transcribed types. A significant reduction in ICC in Scotland should be achieved through the HPV immunisation programme.Keywords
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