One hundred ninety-three cultures of marrows were studied for the presence of fungi. Many of the cases studied had one or more of the classical conditions of histoplasmosis, such as anemia, leukopenia, splenomegaly, hepatomegaly, irregular elevations in temperature, pulmonary disease, and generalized lymphadenopathy. Histoplasma capsulatum was found in only one case. Considering the high incidence of histoplasmin reactors in this locality, it appears that routine cultures of the marrow for Histoplasma capsulatum have little value in histoplasmosis case findings.