ANTIBODIES AGAINST STAPHYLOCOCCUS AUREUS IN NONIMMUNIZED RABBITS

Abstract
Two distinct staphylococcal antibodies were demonstrated in the sera of nonimmunized specific-pathogen-free rabbits. One is responsible for agglutination of S. aureus Cowan serotype I, and the other for the formation of a reaction line observed in Ouchterlony plates with soluble antigens of both Cowan serotypes I and III. Fluorescent antibody reagent prepared from preimmune rabbit serum stained some strains of coagulase positive staphylococci, including Cowan''s types I and III, and failed to stain any of 14 coagulase negative strains.