HEMODYNAMIC CHANGES AT REST AND DURING EXERCISE IN LONG‐TERM β‐BLOCKER THERAPY OF ESSENTIAL HYPERTENSION
- 12 January 1974
- journal article
- Published by Wiley in Acta Medica Scandinavica
- Vol. 195 (1-6), 117-121
- https://doi.org/10.1111/j.0954-6820.1974.tb08107.x
Abstract
In 10 men with untreated early essential hypertension oxygen consumption and central hemodynamics have been studied before and after one year on alprenolol, 400–800 mg daily. The most important changes (at rest and during exercise) induced by therapy were: marked reduction in heart rate and cardiac index, moderate reduction in arterial blood pressure and no change or increase in calculated total peripheral resistance. No subject demonstrated an unequivocal change in hemodynamic pattern towards reduction in total peripheral resistance without decrease in cardiac output.This publication has 20 references indexed in Scilit:
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