HETEROGENEITY OF RABBIT ANTIBODY AND ITS SUBUNITS
- 1 January 1962
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 48 (1), 49-53
- https://doi.org/10.1073/pnas.48.1.49
Abstract
A papain digest of the 0.06M fraction of whole gamma globulin yields a large amount of fraction I and little fraction II, whereas the reverse is true of the 0.5M fraction of gamma globulin. The amount of fraction III obtained was nearly the same in both. If fractions I and II represented different parts of the same molecules, equal quantities of the fractions should be obtained, regardless of the source. It thus appears that fractions I and II are derived from different globulin molecules.Keywords
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