DIRECT ESTIMATES OF CHLORIDE ACTIVITY IN MUSCLE FIBRES DEPOLARIZED BY CARBACHOL
Open Access
- 1 June 1974
- journal article
- Published by Wiley in British Journal of Pharmacology
- Vol. 51 (2), 304-306
- https://doi.org/10.1111/j.1476-5381.1974.tb09661.x
Abstract
Intracellular chloride activities have been measured in muscle fibres with chloride-sensitive electrodes. It was found that the depolarization induced by carbachol produces an influx of chloride ions, the accumulation of which leads to further sustained depolarization. The present study thus confirms the evidence put forward by Jenkinson & Terrar (1973) of an influence of chloride ions on the membrane potential after a prolonged application of carbachol.Keywords
This publication has 12 references indexed in Scilit:
- Influence of chloride ions on changes in membrane potential during prolonged application of carbachol to frog skeletal muscleBritish Journal of Pharmacology, 1973
- The voltage dependence of the chloride conductance of frog muscleThe Journal of Physiology, 1972
- Ion Specific Liquid Ion Exchanger MicroelectrodesAnalytical Chemistry, 1971
- The pH sensitivity of the chloride conductance of frog skeletal muscleThe Journal of Physiology, 1967
- The effect of pH on the 36Cl efflux from frog skeletal muscleThe Journal of Physiology, 1967
- The potassium and chloride conductance of frog muscle membraneThe Journal of Physiology, 1962
- Contractures and permeability changes produced by acetylcholine in depolarized denervated muscleThe Journal of Physiology, 1961
- The influence of potassium and chloride ions on the membrane potential of single muscle fibresThe Journal of Physiology, 1959