Glutamic‐Oxalacetic Transaminase Activity in Spinal Fluid

Abstract

Glutamic-oxalacetic transaminase activity was determined in the spinal fluid and serum by the method of Karmen. In 45 controls, spinal fluid transaminase activity ranged from 5 to 21 units while serum activity ranged from 9 to 33 units. Elevated spinal fluid transaminase values were found in 12 of 104 neurological patients. Elevated values occurred in 4 of 4 patients with subarachnoid bleeding and in 3 of 14 with acute non-hemorrhagic cerebral vascular accidents. No correlation was found between spinal fluid transaminase and spinal fluid protein or between spinal fluid and serum transaminase values.