The presence of a lipoma in the anterior mediastinum, weighing 17 pounds 6 ounces, is so unusual that I wish to record my notes of a case in full. REPORT OF CASE R. K. B., aged 37⅓ years, American; clergyman; married. Family history negative. Aside from diseases of childhood, patient was a healthy child and an athletic boy. At 16 he was kicked in the abdomen by a horse, and his recollection of this was a feeling of distress, at times, for about one year. Never had an injury of the chest; never had pleurisy, pneumonia or pericarditis. He had a deep cough, similar to the one developed with the last illness, about five years before, lasting about a month. Present Illness. —Patient was well until about seventeen months ago when he sought medical advice for a deep, hollow cough which appeared while in apparent physical fitness. Gradually, this cough