Inhibition of Carbonic Anhydrase by Anions in the Carbon Dioxide-Bicarbonate System
- 24 February 1978
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 199 (4331), 907-909
- https://doi.org/10.1126/science.199.4331.907
Abstract
Chloride and iodide ions exhibit noncompetitive inhibition of carbon dioxide hydration catalyzed by bovine carbonic anhydrase and competitive inhibition of bicarbonate dehydration. Consideration of the net velocity at equilibrium leads to a satisfactory resolution of the dilemma concerning the different concentrations of such anions required to halve the initial reaction rate for each substrate.Keywords
This publication has 5 references indexed in Scilit:
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- Inhibition by Anions of Human Red Cell Carbonic Anhydrase B: Physiological and Biochemical ImplicationsScience, 1976
- Inhibition by Anions of Human Red Cell Carbonic Anhydrase B: Physiological and Biochemical ImplicationsScience, 1976
- Kinetic studies of bovine carbonic anhydrase catalyzed hydrolyses of p-substituted phenyl estersBiochemistry, 1972
- The Carbon Dioxide Hydration Activity of Carbonic AnhydraseJournal of Biological Chemistry, 1971