A model from electron microscopy for the molecular structure of fibrinogen and fibrin
- 1 January 1981
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 289 (5795), 263-267
- https://doi.org/10.1038/289263a0
Abstract
The overall architecture of the fibrinogen molecule and aspects of its packing to form fibrin were derived from a study of EM images of ordered arrays. The molecule, of length 450 .ANG., is seen in more detail than the Hall-Slayter model and is made up of 7 globular domains connected by rod-like segments. [The model developed should allow for better understanding of human and bovine fibrin and fibrinogen.].Keywords
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