The Structure of Fowl-Pox Inclusions (Bollinger Bodies)

Abstract

The cytoplasmic inclusion bodies produced by fowl-pox virus in the chorioallantoic membrane of the egg consist of a mass of virus particles, frequently surrounding an apparently normal component of the cytoplasm. Finely granular or filamentous material is seen in the centre of the inclusion and round the more central virus particles into whose structure it appeared to be incorporated. The inner virus bodies consisted of a granular core surrounded by a single membrane. The outer virus bodies consisted of a cortical layer 20 mμ thick, enclosing a space in which lay a core with a granular centre.