Synthesis and antiallergic activity of some mono- and disubstituted xanthone-2-carboxylic acids
- 1 July 1978
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 21 (7), 669-672
- https://doi.org/10.1021/jm00205a014
Abstract
A series of xanthone-2-carboxylic acids, substituted mainly with electron-withdrawing groups, was synthesized and assayed for anti-allergic activity, using the passive cutaneous anaphylaxis (PCA) reaction in the rat. The effect of substituent type and substitution pattern on PCA neutralizing capacity was presented.This publication has 1 reference indexed in Scilit:
- A Simple Modification of the Wolff-Kishner ReductionJournal of the American Chemical Society, 1946