ADRENOCORTICOTROPIC SUBSTANCES FROM HUMAN PLACENTA1
- 1 November 1954
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 55 (5), 561-567
- https://doi.org/10.1210/endo-55-5-561
Abstract
Four fractions obtained from human placental tissue and from blood contained in the intervillous space were assayed for adrenocorticotropic activity by the ascorbic acid depletion method. Fractions D and B, which were prepared by the oxycellulose technique from dried chorionic villi and from intervillous blood respectively, showed a striking corticotropic activity. The activity of 0.15 mg of fraction D was found to be comparable to that of 1 milliunit of the standard USP corticotropin.Keywords
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