Identifizierung von Überträgern der chronischseptischen Granulomatose*: Bestimmung der Superoxid-Radikal-Bildung
- 1 January 1980
- journal article
- research article
- Published by Georg Thieme Verlag KG in Deutsche Medizinische Wochenschrift (1946)
- Vol. 105 (52), 1814-1816
- https://doi.org/10.1055/s-2008-1070965
Abstract
Chronic granulomatous disease is caused by an X chromosome-linked granulocyte function defect whereby the superoxide radical (O2-) and hydrogen peroxide are not formed during phagocytosis. During the investigation of the family of a boy with chronic granulomatosis disease carriers could not be established using the NBT [nitro-blue tetrazolium] test. Only determination of O2- formation by granulocytes during phagocytosis led to identification of disease carriers. This may possibly represent a means for prenatal diagnosis.This publication has 5 references indexed in Scilit:
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