Stimulation of calcium uptake into aortic microsomes by cyclic AMP and cyclic AMP-dependent protein kinase
- 1 July 1977
- journal article
- conference paper
- Published by Springer Nature in Naunyn-Schmiedebergs Archiv für experimentelle Pathologie und Pharmakologie
- Vol. 298 (3), 255-257
- https://doi.org/10.1007/bf00500896
Abstract
Enhancement of calcium uptake into rabbit aortic microsomes was seen at a cyclic AMP concentration of 10−6M in the presence of cyclic AMP-dependent protein kinase (ATP: protein phosphotransferase, EC 2.7.1.37). Protein kinase alone also increased calcium uptake, but cyclic AMP alone was without effect. The results suggest that stimulation of calcium sequestration may be the mechanism of cyclic AMP involvement in vascular smooth muscle relaxation.This publication has 12 references indexed in Scilit:
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