Trial of an Alpha‐adrenolytic Drug (Indoramin) for Nocturnal Enuresis

Abstract
The investigation of methods of treatment known to be effective in controlling nocturnal enuresis may yield information on the pathophysiology of the condition. An attempt was made to mimic the known .alpha.-adrenolytic action of imipramine by treating a group or 14 enuretic school children with a competitive .alpha.-adrenoceptor blocking substance, indoramin. Treatment in the doses used had no significant effect on night wetting frequency.