C-band polymorphism in human chromosome no. 6

Abstract
Chromosome analysis of G[Giemsa]-banded cells from 92 individuals consecutively referred to the Cytogenetics Laboratory show that the paracentromeric band in the short arm (6p11), which stains negatively with G-banding and darkly with C[constitutive heterochromatin]-banding, shows a marked increase in size in about 9% of chromosomes 6. The results of this study and those from a family in which 2 variants of chromosome 6 are segregating are compatible with a Mendelian pattern of inheritance.