Effect of Scurvy on Hexokinase Activity of Tissues of Guinea Pigs
- 1 March 1955
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 88 (3), 415-416
- https://doi.org/10.3181/00379727-88-21604
Abstract
Hexokinase activity of the liver, muscle, pancreas and kidney of both scorbutic and pair fed, normal guinea pigs was determined. A significant decrease in the hexokinase activity of the liver and skeletal muscle was observed in scorbutic guinea pigs. No change in the hexokinase activity was observed in the pancreas while the same in the kidney was considerably increased during scurvy. The diminished insulin formation in the scorbutic guinea pigs might be responsible for the decreased hexokinase activity in the muscle and liver in scurvy.Keywords
This publication has 9 references indexed in Scilit:
- Biosynthesis of Ascorbic Acid and Prevention of Glycogen Depletion in Liver and MuscleExperimental Biology and Medicine, 1954
- Tissue Glycogen Storage as Affected by AcetoacetateExperimental Biology and Medicine, 1953
- Studies on alloxan diabetes. 1. Increase of susceptibility caused by acetoacetateBiochemical Journal, 1953
- Progressive depletion in the reduced glutathione content of the blood following acetoacetate injectionsBiochemical Journal, 1953
- Progressive Decreased Glucose-tolerance and Glycogen-storage Following Acetoacetate Injection; Prevention by Insulin and AmellinExperimental Biology and Medicine, 1950
- URIC ACID DIABETES1948
- Protective Effect of Glutathione and Cysteine Against Alloxan Diabetes in the Rat.Experimental Biology and Medicine, 1946
- Inactivation of Insulin by Intermediary Fat Metabolism ProductsNature, 1946
- Experimental Hyperglycæmia by Injection of Intermediary Fat Metabolism Products in RabbitsNature, 1944