Hypothalamic Norepinephrine: Circadian Rhythms and the Control of Feeding Behavior
- 10 November 1972
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 178 (4061), 640-643
- https://doi.org/10.1126/science.178.4061.640
Abstract
The time of day is a decisive determinant of the effects of l-norepinephrine on feeding behavior. During the dark, direct application of l-norepinephrine to the hypothalamus of rats suppressed feeding behavior. During the light, treatment with the same dose of l-norepinephrine facilitated feeding behavior. Thus, l-norepinephrine has dual and opposite effects on feeding behavior. A hypothalamic substrate that fluctuates in a circadian rhythm could account for both actions of l-norepinephrine.Keywords
This publication has 13 references indexed in Scilit:
- Norepinephrine: Reversal of Anorexia in Rats with Lateral Hypothalamic DamageScience, 1971
- Circadian ChronopharmacologyAnnual Review of Pharmacology, 1971
- Feeding: Neural Control of IntakeAnnual Review of Physiology, 1971
- Light-dark rhythms in rat eating and drinking behaviorPhysiology & Behavior, 1971
- Hypothalamic β-Adrenergic “Satiety” System antagonizes an α-Adrenergic “Hunger” System in the RatNature, 1970
- Alpha-adrenergic receptors in hypothalamus for the suppression of feeding behavior by satiety.Journal of Comparative and Physiological Psychology, 1970
- Feeding patterns of normal and ventromedial hypothalamic lesioned male and female rats.Journal of Comparative and Physiological Psychology, 1970
- Daily Rhythm in the Noradrenaline Content of Rat HypothalamusNature, 1968
- Light-Induced Changes in Pineal Hydroxyindole- O -Methyltransferase: Abolition by Lateral Hypothalamic LesionsScience, 1966
- A demonstration of a fall in brain serotonin following central nervous system lesions in the ratBiochemical Pharmacology, 1962