MORPHOLOGICAL AND BIOCHEMICAL CHANGES IN THE GASTRIC MUCOSA OF A/HEJ MICE INJECTED WITH A XENOGENEIC STOMACH ANTIGEN
- 1 November 1977
- journal article
- research article
- Published by Wiley in Acta Pathologica Japonica
- Vol. 27 (6), 869-876
- https://doi.org/10.1111/j.1440-1827.1977.tb03041.x
Abstract
S.c. injection of W/Fu rat stomach antigen emulsified with an equal volume of Freund''s complete adjuvant at 1 wk interval for a total of 2 administrations induced atrophic gastritis in A/HeJ mice. From the 2nd wk after the last injection the parietal cell mass decreased. At the same time, Alcian blue-PAS [periodic acid-Schiff] positive cells and Paneth-like cells appeared. The activity of alkaline phosphatase and disaccharidase of the small intestinal mucosa was biochemically demonstrated in the atrophic glandular stomach.This publication has 14 references indexed in Scilit:
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