ELEVATED PLATELET-BOUND IGG ASSOCIATED WITH AN EPISODE OF THROMBOTIC THROMBOCYTOPENIC PURPURA
- 1 January 1981
- journal article
- research article
- Vol. 58 (4), 682-684
Abstract
The level of platelet-associated IgG (PAIgG) was measured during the successful treatment of a patient with thrombotic thrombocytopenic purpura. Prior to therapy, PAIgG was markedly elevated to 195 fg[femtograms]/cell (normal range 0-3.5 fg/cell). The institution of combined therapy with intensive plasma exchange transfusions, high-dose steroids and antiplatelet drugs resulted in a complete recovery and a decline in PAIgG to the normal range. The possible role of platelet antibody in the pathogenesis of this disorder is discussed.This publication has 11 references indexed in Scilit:
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