Growth Requirements of Saccharomyces cerevisiae as a Result of Incubation at Increased Temperature.

Abstract

Summary Data were presented which revealed that the paucity of growth of a mutant strain of yeast at 38°C is not only related to an inability to carry out the biosynthesis of pantothenic acid but also the requirement for an increased osmotic pressure or perhaps simply a high solute concentration. Results were discussed in terms of possible mechanisms by which these environmental conditions might serve to permit growth of the mutant at increased incubation temperatures. Since at lower temperatures the organism is genetically capable of synthesizing pantothenic acid, the role of environment in genetic expression is reemphasized.