PoPMuSiC 2.1: a web server for the estimation of protein stability changes upon mutation and sequence optimality
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Open Access
- 13 May 2011
- journal article
- Published by Springer Nature in BMC Bioinformatics
- Vol. 12 (1), 151
- https://doi.org/10.1186/1471-2105-12-151
Abstract
The rational design of modified proteins with controlled stability is of extreme importance in a whole range of applications, notably in the biotechnological and environmental areas, where proteins are used for their catalytic or other functional activities. Future breakthroughs in medical research may also be expected from an improved understanding of the effect of naturally occurring disease-causing mutations on the molecular level.Keywords
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