STUDIES ON THE LEUKOCYTOSIS AND LYMPHOCYTOSIS INDUCED BY BORDETELLA PERTUSSIS
Open Access
- 1 March 1967
- journal article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 125 (3), 401-408
- https://doi.org/10.1084/jem.125.3.401
Abstract
By the use of radioautographic techniques it was shown that the lymphocytosis induced by Bordetella pertussis in mice was not caused by an increased production of lymphocytes but was primarily due to the entry into the circulation of mature cells from tissue pools. The accompanying polymorphonuclear leukocytosis was due to both proliferation of myeloid elements and entry of mature cells from tissue reserves, with the former the predominant mechanism.Keywords
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