Myeloid and Erythroid Colony Growth in Non-anaemic Patients with Fanconi's Anaemia

Abstract
Myeloid and erythroid colony growth of the bone marrow and peripheral blood cells from 1 anemic and 4 non-anemic patients with Fanconi''s anemia were studied. Markedly decreased myeloid and erythroid colony growth was found in all 5 patients regardless of their hematological status. The decreased colony formation in non-anemic patients with Fanconi''s anemia may be due to an intrinsic cellular defect.