The neurotoxicity of 1-methyl-4-phenyl-1,2,3,6,-tetrahydropyridine (mptp) and its relevance to parkinson's disease
- 31 December 1987
- journal article
- review article
- Published by Elsevier in Neurochemistry International
- Vol. 11 (4), 359-373
- https://doi.org/10.1016/0197-0186(87)90024-6
Abstract
No abstract availableKeywords
This publication has 98 references indexed in Scilit:
- N‐Methyl‐4‐Phenyl‐1,2,3,6‐Tetrahydropyridine Increases Acetylcholine and Decreases Dopamine in Mouse Striatum: Both Responses Are Blocked by Anticholinergic DrugsJournal of Neurochemistry, 1985
- A catalyst function for MPTP in superoxide formationBiochemical and Biophysical Research Communications, 1985
- The specific vulnerability of the substantia nigra to MPTP is related to the presence of transition metalsBiochemical and Biophysical Research Communications, 1985
- Reversible inhibition and mechanism-based irreversible inactivation of monoamine oxidases by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)Biochemical and Biophysical Research Communications, 1985
- IV. Differences in the metabolism of MPTP in the rodent and primate parallel differences in sensitivity to its neurotoxic effectsLife Sciences, 1985
- III. Primate model of parkinsonism: Selective lesion of nigrostriatal neurons by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine produces an extrapyramidal syndrome in rhesus monkeysLife Sciences, 1985
- V. Potential bioactivation pathways for the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)Life Sciences, 1985
- Metabolism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in mouse liver preparationsBiochemical and Biophysical Research Communications, 1984
- Oxidation of the neurotoxic amine 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) by monoamine oxidases A and B and suicide inactivation of the enzymes by MPTPBiochemical and Biophysical Research Communications, 1984
- The effect of age on the activity and molecular properties of human brain monoamine oxidaseJournal of Neural Transmission, 1980