ATRESIA AND STENOSIS OF THE AQUEDUCT OF SYLVIUS

Abstract

A study of the cases of atresia or stenosis of the aqueduct of Sylvius disclosed that the defect is probably the result of a blastomatous process congenital in origin rather than secondary to inflammation, toxic agents or trauma. In most cases, there were alterations occurring in the development of the midbrain or about the aqueductal region. It is assumed that the aqueductal occlusion has its origin in the developmental stage of the affected individual. Though at first slow in progress, at a critical moment it serves to block satisfactory passage of cerebrospinal fluid. This in turn causes internal hydrocephalus and the clinical features of increased intracranial tension with focal signs.