Altered Amyloid-β Metabolism and Deposition in Genomic-based β-Secretase Transgenic Mice
Open Access
- 1 December 2004
- journal article
- Published by Elsevier
- Vol. 279 (50), 52535-52542
- https://doi.org/10.1074/jbc.m409680200
Abstract
No abstract availableKeywords
This publication has 52 references indexed in Scilit:
- Transgenic BACE expression in mouse neurons accelerates amyloid plaque pathologyJournal of Neural Transmission, 2004
- The β-amyloid-related proteins presenilin 1 and BACE1 are axonally transported to nerve terminals in the brainExperimental Neurology, 2003
- Specific BACE1 genotypes provide additional risk for late‐onset alzheimer disease in APOE ε4 carriersAmerican Journal Of Medical Genetics Part B-Neuropsychiatric Genetics, 2003
- Neuropathological Characterization of Mutant Amyloid Precursor Protein Yeast Artificial Chromosome Transgenic MiceNeurobiology of Disease, 2001
- Coordinated Expression of β‐Amyloid Precursor Protein and the Putative β‐Secretase BACE and α‐Secretase ADAM10 in Mouse and Human BrainJournal of Neurochemistry, 2000
- Identification of a Novel Aspartic Protease (Asp 2) as β-SecretaseMolecular and Cellular Neuroscience, 1999
- BACE Maps to Chromosome 11 and a BACE Homolog, BACE2 , Reside in the Obligate Down Syndrome Region of Chromosome 21Science, 1999
- Homologous recombination based modification in Esherichia coli and germline transmission in transgenic mice of a bacterial artificial chromsomeNature Biotechnology, 1997
- Introduction and expression of the 400 kilobase precursor amyloid protein gene in transgenic miceNature Genetics, 1993
- Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid proteinBiochemical and Biophysical Research Communications, 1984