Abstract
In virgin oophorectomized guinea pigs studied by palpation and by fluoroscopic examinations, it was found that when they were primed with estrogens, that desoxycorticosterone acetate can substitute for progesterone in bringing about relaxation of the pubic symphysis. Only a few animals showed a degree of relaxation comparable to that obtained in advanced pregnancy. Milk secretion was obtained in many of these guinea pigs.