The tautomeric conversion of p-hydroxyphenylpyruvic acid
- 1 January 1947
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 41 (4), 520-522
- https://doi.org/10.1042/bj0410520
Abstract
In aqueous soln., the conversion of p-hydroxyphenylpyruvic acid from the enolic to the ketonic form was greatly accelerated in alkaline soln. In guinea-pig urine, the conversion to the ketonic form took place more rapidly than in water at all values of pH investigated. Probably the conversion proceeds in guinea-pig tissue at a rate similar to that in urine. In both cases, approx. 99% of the p-hydroxyphenylpyrmdc acid existed in the ketonic form. The detn. of p-hydroxy-phenylpyruvic acid in guinea-pig urine by the Briggs reaction or by indophenol titration does not yield satisfactory results, but the Penrose and Quastel reaction is reliable.Keywords
This publication has 5 references indexed in Scilit:
- The influence of l-ascorbic acid on the rupture of the benzene ring of l-tyrosine consumed in high doses by guinea-pigsBiochemical Journal, 1947
- The determination of 2:3-diketo-l-gulonic acidBiochemical Journal, 1943
- Metabolic studies in phenylketonuriaBiochemical Journal, 1937
- A new error of tyrosine metabolism: tyrosinosis. The intermediary metabolism of tyrosine and phenylalanineBiochemical Journal, 1932
- The Tyrosinase-Tyrosine Reaction. IIBiochemical Journal, 1925