CHEMICAL, CLINICAL, AND IMMUNOLOGICAL STUDIES ON THE PRODUCTS OF HUMAN PLASMA FRACTIONATION. XVIII. FIBRINOGEN COAGULUM AS AN AID IN THE OPERATIVE REMOVAL OF RENAL CALCULI 1

Abstract

A new aid in the removal of small free stones from the renal pelvis at open operation is described. By the simultaneous inj. of solns. of fibrinogen and thrombin, a strong coagulum which completely fills the pelvis and enmeshes all free stones is produced. On withdrawing this coagulum through the usual pyelotomy incision, all free stones should be removed. Fragmentation of calculi and trauma to the kidney are thus avoided. This operative procedure has been carried out in 21 patients without demonstrable ill effect. The operative results herein reported, although still imperfect, are improving as additional experience with the method is acquired. It is hoped that this procedure will be of distinct aid in the problem of the surgical removal of renal calculi.