Gestational diabetes and offspring body disproportion
- 8 December 2009
- journal article
- Published by Wiley in Acta Paediatrica
- Vol. 99 (1), 89-93
- https://doi.org/10.1111/j.1651-2227.2009.01532.x
Abstract
It has been demonstrated that females born large for gestational age (LGA) in weight but not length are at increased risk of being obese at childbearing age. We addressed the question whether women with gestational diabetes mellitus (GDM) are at increased risk of giving birth to such infants. Birth characteristics of 884,267 infants of non-diabetic mothers and 7817 of mothers with GDM were analysed. LGA was defined as birth weight or birth length >2 standard deviation scores for gestational age. Multiple logistic regression analysis was performed. The odds ratio (OR) for a woman with GDM to give birth to an LGA infant that was heavy alone was four times increased (OR: 3.71, 95% CI: 3.41-4.04). Furthermore, in the population of mothers giving birth to LGA infants, the proportion heavy alone was 68% in the group of women with GDM compared with 64.4% in the group of non-diabetic women. The risks were independent of gender of the foetus. Women with GDM have an almost four times higher risk of delivering an LGA infant that is heavy alone. The noted disproportion between weight and length in infants of such mothers may have an impact on the risk of later obesity.Keywords
This publication has 24 references indexed in Scilit:
- Maternal glucose tolerance status influences the risk of macrosomia in male but not in female fetusesJournal of Epidemiology and Community Health, 2009
- The impact of birth weight on prostate cancer incidence and mortality in a population‐based study of men born in 1913 and followed up from 50 to 85 years of ageThe Prostate, 2007
- Females born large for gestational age have a doubled risk of giving birth to large for gestational age infantsActa Paediatrica, 2007
- Fetal and Neonatal Outcomes of Diabetic PregnanciesObstetrics & Gynecology, 2006
- Long‐Term Safety and Efficacy of Circumferential Ablation with Pulmonary Vein IsolationJournal of Cardiovascular Electrophysiology, 2006
- Metabolic Syndrome in Childhood: Association With Birth Weight, Maternal Obesity, and Gestational Diabetes MellitusPediatrics, 2005
- Reasons for Increasing Trends in Large for Gestational Age BirthsObstetrics & Gynecology, 2004
- The influence of obesity and diabetes on the prevalence of macrosomiaAmerican Journal of Obstetrics and Gynecology, 2004
- Anthropometric differences in macrosomic infants of diabetic and nondiabetic mothersThe Journal of Maternal-Fetal Medicine, 1998
- WEIGHT AND LENGTH AT BIRTH OF INFANTS OF DIABETIC MOTHERSActa Endocrinologica, 1954