Mutagenicity of HPLC fractions from extracts of aatrex‐treated corn

Abstract

Crude extracts from maize plants treated with varying concentrations of AAtrex, an s‐triazine herbicide, were tested for the induction of gene conversion in a diploid strain of Saccharomyces cerevisiae heteroallelic at two loci. These extracts were then subjected to analysis by high pressure liquid chromatography (HPLC), and the fractions collected in water, 50% methanol, and 100% methanol were similarly tested. Dose‐dependent convertogenic activity observed in the 50% methanol fractions suggested that the mutagen(s) is recovered in this fraction.