MEASUREMENT OF INTERVILLOUS AND MYOMETRIAL BLOOD FLOW BY AN INTRAVENOUS 133Xe METHOD
- 1 September 1976
- journal article
- Published by Wiley in BJOG: An International Journal of Obstetrics and Gynaecology
- Vol. 83 (9), 723-728
- https://doi.org/10.1111/j.1471-0528.1976.tb00921.x
Abstract
A new ‘non-invasive’ method for measuring intervillous and myometrial blood flow is presented. After 2 mCi of 133Xe in physiological saline was injected intravenously the patient held her breath for 20 seconds. The tracer entered the placenta as a short bolus and its removal was followed with a scintillation detector. Intervillous and myometrial blood flow per unit volume was calculated from the two-exponential curve. The mean ±SD intervillous flow in normal pregnancy was 135±49 ml/minute/100 ml, the corresponding half time being 0·56±0·16 minutes. The myometrial flow was 7 ·7±2·5 ml/minute/100 g. The method gave reproducible results and took only 20 minutes to perform. The dose of radiation to the mother was less than 1 mrad.Keywords
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