BIOCHEMICAL STUDIES OF TOXIC AGENTS. THE METABOLISM OF IODOMETHANE
- 1 April 1965
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 95 (1), 77-81
- https://doi.org/10.1042/bj0950077
Abstract
The metabolism of iodomethane was studied after the administration of the compound to rats by subcutaneous injection. The urinary excretion of S-methylcysteine, methylmercapturic acid, methylthioacetic acid and N-(methylthioacetyl)glycine was demonstrated by paper chromatography. Methylmercapturic acid and N-(methylthioacetyl)glyclne was isolated from the urine of the dosed animals. The methylthio compounds detected represented about 2% of the iodomethane administered.Keywords
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