THE PENETRATION OF SUGARS INTO THE AQUEOUS HUMOUR

Abstract

The conc. of sugar in the blood of dogs as judged by the reducing value before and after hydrolysis was raised to 2 or 3 times the normal level by the continuous inj. of a soln. of xylose, glucose, sucrose or raffinose. The conc. of these sugars in the aqueous humor was detd. after different periods of inj. Xylose and glucose entered the aqueous humor almost immediately and increased rapldly in conc. The entrance of sucrose was delayed about 1/2 hr. and only a trace of raffinose appeared in the aqueous humor even after 3 hrs. Thus, raffinose represents the limit of the size of a lipoid-insoluble, non-electrolyte molecule entering the eye.