Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China

Abstract

In December 2019, many unexplained pneumonia cases occurred in Wuhan, China, and rapidly spread to other parts of China, then to Europe, North America, and Asia. This outbreak was confirmed to be caused by a novel coronavirus (CoV).¹ The novel CoV was reported to have symptoms resembling that of severe acute respiratory syndrome CoV (SARS-CoV) in 2003.² Both shared the same receptor, angiotensin-converting enzyme 2 (ACE2).³ Therefore, this virus was named SARS-CoV-2, and in February 2020, the World Health Organization (WHO) named the disease coronavirus disease 2019 (COVID-19). As of March 5, 2020, there were 95 333 confirmed cases of COVID-19 and 3282 deaths globally.⁴