GENETIC-EVIDENCE FOR THE INACTIVATION OF A HUMAN AUTOSOMAL LOCUS ATTACHED TO AN INACTIVE X-CHROMOSOME
- 1 January 1982
- journal article
- research article
- Vol. 34 (5), 811-817
Abstract
Mouse-human cell hybrid clones retaining an inactive translocated chromosome involving the human X and 13 were isolated. Esterase D, a marker on the segment of chromosome 13 translocated to the X, was not expressed in these clones. These results provide genetic evidence for the spreading of inactivation into the autosomal segment in an inactive human X-autosome translocation.This publication has 23 references indexed in Scilit:
- Regional Assignment of Genes for Human Esterase D and Retinoblastoma to Chromosome Band 13q14Science, 1980
- Retinoblastoma with 13q- Chromosomal Deletion Associated with Maternal Paracentric Inversion of 13qScience, 1979
- Human and Mouse Hypoxanthine-Guanine Phosphoribosyltransferase: Dimers and TetramersScience, 1979
- Chromosomal anomalies in patients with retinoblastomaClinical Genetics, 1977
- Chromosome assignment of some human enzyme loci: mitochondrial malate dehydrogenase to 7, mannosephosphate isomerase and pyruvate kinase to 15 and probably, esterase D to 13Annals of Human Genetics, 1975
- Assignment of human esterase-D gene to chromosome 13Cytogenetic and Genome Research, 1975
- Esterase D: a new human polymorphismAnnals of Human Genetics, 1973
- G6PD Expression and X Chromosome Late Replication in Fibroblast Clones from a Female MuleNature, 1972
- Further Proof of Genetic Inactivation of the X Chromosome in the Female MuleNature, 1972
- Selection of Hybrids from Matings of Fibroblasts in vitro and Their Presumed RecombinantsScience, 1964