Effects of Vasoactive Intestinal Polypeptide on Resistance and Capacitance Vessels in the Nasal Mucosa

Abstract
Vasoactive intestinal polypeptide (VIP) im-munoreactive nerves have previously been demonstrated in the feline nasal mucosa. In the present investigation it isshown that VIP given close arterially dilates both resistance and capacitance vessels in the nose of the cat. This vasodilatation is atropine resistant. It is suggested that VIP serves a physiological role in the neurogenic control of blood vessels in the nasal mucosa.