ACTION OF TESTOSTERONE ON THE FEMALE RAT HYPOPHYSIS1,

Abstract

The pituitary glands of adult [female] rats treated with testosterone propionate exhibit a decrease in gonad-stimulating potency when implanted into immature mice. There is no difference in this effect whether the donor receives the first inj. of the [male] hormone at estrus or at diestrus. This lessened gonadotrophic activity is considered the result of an inhibition of the luteinizing hormone while normal follicle-stimulating hormone production is maintained.